S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia

Opposing effect of H2O2 in the regulation of STAT1 and STAT3 signaling. This scheme provides a representation of STAT1 and STAT3 pathways regulation under oxidative stress. It evidences the opposing role of S-glutathionylation in the redox regulation of STAT1 and STAT3 signaling.155