Genetic variants of the APE1 gene and the risk of vitiligo in a Chinese population: A genotype-phenotype correlation study

► Associations between variants of APE1 and the risk of vitiligo were investigated. ► The SNP rs3136820 was significantly associated with the risk of vitiligo. ► The Glu variant interacted with higher 8-OHdG levels in the deleterious effects. ► The Glu variant increases oxidative DNA damage and influences the risk of vitiligo.