Oxidative modification of patient's plasma proteins and its role in pathogenesis of multiple sclerosis

► We estimate markers of oxidative/nitrosative stress in multiple sclerosis (MS). ► We show differences between two main types of MS. ► Level of plasma carbonyl groups was elevated in both types of MS. ► Level of 3-NT was higher in secondary progressive than relapsing-remitting MS. ► Level of uric acid was lower in relapsing-remitting than secondary progressive MS.