کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8333552 | 1540261 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
α-d-Glucosidase inhibitory activity of polysaccharide isolated from Acacia tortilis gum exudate
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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![عکس صفحه اول مقاله: α-d-Glucosidase inhibitory activity of polysaccharide isolated from Acacia tortilis gum exudate α-d-Glucosidase inhibitory activity of polysaccharide isolated from Acacia tortilis gum exudate](/preview/png/8333552.png)
چکیده انگلیسی
The study aims to explore the antihyperglycemic activity of Acacia tortilis polysaccharide isolated from the gum exudate. α-d-Glucosidase from Saccharomyces cerevisiae and rat small intestine was used as in vitro model to assess α-d-glucosidase inhibitory activity of the polysaccharide against yeast and mammalian enzyme. The reduction in postprandial blood glucose level after carbohydrate rich diet fed to Albino Wistar rats was employed as in vivo model of α-d-glucosidase inhibition. The study revealed α-d-glucosidase inhibitory activity of the polysaccharide in both in vitro as well as in vivo models. Therefore, polysaccharide isolated from A. tortilis plant gum exudate may be a potential drug for diabetes mellitus and its complications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 59, August 2013, Pages 214-220
Journal: International Journal of Biological Macromolecules - Volume 59, August 2013, Pages 214-220
نویسندگان
Swati Bisht, Ravi Kant, Vineet Kumar,