کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8334000 | 1540268 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibacterial activity evaluation of quaternary chitin against Escherichia coli and Staphylococcus aureus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
Water-soluble quaternary chitin/chitosan derivatives, O-[(2-hydroxy-3-trimethylammonium)propyl chitin (OHT-chitin), N-[(2-hydroxy-3-trimethylammonium)propyl chitosan (NHT-chitosan), and N,N,N-trimethylchitosan (TMC), having identical molecular weight and same anion, were prepared, and their antibacterial activities against Escherichia coli and Staphylococcus aureus were evaluated. Their minimum inhibitory concentration (MIC) values varied from 0.04Â mg/mL to 20.48Â mg/mL, and the minimum bactericidal concentration (MBC) values varied from 0.16Â mg/mL to 40.96Â mg/mL against E. coli and S. aureus, respectively. Transmission electron microscopy (TEM) clearly showed that there was serious damage on the bacterial walls, whereas there was some dissimilarity between TMC-treated E. coli and S. aureus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 52, January 2013, Pages 85-91
Journal: International Journal of Biological Macromolecules - Volume 52, January 2013, Pages 85-91
نویسندگان
Jianying Huang, Hengjun Jiang, Miao Qiu, Xiaodong Geng, Ronghua Yang, Jianrong Li, Chaohua Zhang,