Synthesis of gum kondagogu-g-poly(N-vinyl-2-pyrrolidone) and its evaluation as a mucoadhesive polymer

► Gum kondagogu-g-poly(N-vinyl-2-pyrrolidone) was synthesized by UV-assisted method. ► Concentration of N-vinyl pyrrolidone exerted a significant antagonistic influence on grafting. ► Concentration of ammonium persulphate exerted a significant synergistic influence on grafting. ► Buccal discs formulated using gum kondagogu-g-poly(N-vinyl pyrrolidone) showed higher ex vivo bioadhesion time than the discs formulated using gum kondagogu.