کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8334541 1540272 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A new investigation for some steroidal derivatives as anti-Alzheimer agents
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
A new investigation for some steroidal derivatives as anti-Alzheimer agents
چکیده انگلیسی
We herein report the anti-Alzheimer activity of some synthesized heterocyclic pyrimidine and thiopyrimidine derivatives fused with steroidal structure. Twenty-one of these compounds were synthesized and conveniently screened for their anti-Alzheimer activities using of Flurbiprofen as the reference drug. Some of these compounds were demonstrated to exhibit remarkable activity and their β-amyloid (Aβ) lowering results as IC50 values reported.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 51, Issues 1–2, July–August 2012, Pages 56-63
نویسندگان
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