کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8335588 | 1540279 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5â²-(C3TA2)4-3â² sequence of the human telomere
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5â²-(C3TA2)4-3â² sequence of the human telomere Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5â²-(C3TA2)4-3â² sequence of the human telomere](/preview/png/8335588.png)
چکیده انگلیسی
The influence of pH, temperature and the cationic porphyrin TMPyP4 on the conformational equilibria of the cytosine-rich strand of the human telomeric sequence 5â²-(C3TA2)4-3â², as well as those of the sequence 5â²-(C3TT2)4-3â², was studied. The presence of adenine bases at the loops causes the formation of two different intramolecular i-motif structures with a pH-transition midpoint around 4.6, which stability is lower than the i-motif formed by the sequence 5â²-(C3TT2)4-3â². The stoichiometries of the complexes formed by these i-motif structures with TMPyP4 are also influenced by the presence of adenine at the loops.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 49, Issue 4, 1 November 2011, Pages 729-736
Journal: International Journal of Biological Macromolecules - Volume 49, Issue 4, 1 November 2011, Pages 729-736
نویسندگان
Sergio Fernández, Ramon Eritja, Anna Aviñó, Joaquim Jaumot, Raimundo Gargallo,