کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8336066 | 1540285 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Radiation crosslinking polymerization of sterculia polysaccharide-PVA-PVP for making hydrogel wound dressings
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Radiation crosslinking polymerization of sterculia polysaccharide-PVA-PVP for making hydrogel wound dressings Radiation crosslinking polymerization of sterculia polysaccharide-PVA-PVP for making hydrogel wound dressings](/preview/png/8336066.png)
چکیده انگلیسی
The present study deals with the modification of sterculia gum by PVA-PVP through radiation crosslinking, to develop the hydrogels meant for the delivery of antimicrobial agent to the wounds. The hydrogels were characterized by SEM, FTIR, TGA and swelling studies. For the evaluation of swelling and drug release mechanism, the swelling kinetics and in vitro release dynamics of model drug from this matrix have been studied respectively in the solution of different pHs and simulated wound fluid. After 24 h swelling per gram of the hydrogel has taken (17.03 ± 0.19)g of simulated wound fluid and has released (0.230 ± 0.01)mg of drug in the simulated fluid. The release of drug in simulated fluids occurred through non-Fickian diffusion mechanism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 48, Issue 3, 1 April 2011, Pages 501-510
Journal: International Journal of Biological Macromolecules - Volume 48, Issue 3, 1 April 2011, Pages 501-510
نویسندگان
Baljit Singh, Lok Pal,