IbACP, a sixteen-amino-acid peptide isolated from Ipomoea batatas leaves, induces carcinoma cell apoptosis

► A 16-amino-acid peptide, IbACP, was isolated from leaves of sweet potato. ► IbACP contained no post-translational modifications and caused an alkalinizing response with plant cell media. ► IbACP regulated cellular proliferation and demonstrated anti-cancer effects via apoptosis.