Minireview: Mode of action of meta-diamide insecticides

- Meta-diamides are antagonists effective against A2′ mutant RDL GABA receptors.
- The meta-diamide site of action is different from that of conventional NCAs.
- The meta-diamide site of action may overlap with that of the macrocyclic lactones.
- The meta-diamides and macrocyclic lactones have different modes of action.
- The meta-diamides are prominent insecticides with unique features.