Keywords: گابار; Aβ; amyloid-β; BBB; blood-brain-barrier; CaMKII; calcium calmodulin kinase II; CFC; contextual fear conditioning test; DAG; diacylglycerol; F3; fibronectin type III module; FGFR; fibroblast growth factor receptor; GABAAR; γ-aminobutyric acid A recept
مقالات ISI گابار (ترجمه نشده)
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Keywords: گابار; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Arc; activity-regulated cytoskeletal-association protein; BDNF; bone-derived neurotrophic factor; CaMK; Ca2+/calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate;
Keywords: گابار; aPC; Anterior piriform cortex; GABAAR; GABAA receptor; K-S; Kolmogorov-Smirnov test; LOT; Lateral olfactory tract; mIPSC; Miniature inhibitory postsynaptic current; P; Postnatal day; sIPSC; Spontaneous inhibitory postsynaptic current; TTX; Tetrodotoxin; K
Keywords: گابار; Pentameric ligand-gated ion channel; GLIC; GABAA receptor; Chimera; Anesthetics; Neurosteroid; Propofol; Etomidate; Pentobarbital; THDOC; Allosteric drug modulation; pLGIC; pentameric ligand-gated ion channel; GABAAR; gamma amino butyric acid type A recep
Keywords: گابار; Astroglial signaling and metabolism; Astrocytic control of excitation; Astrocytic energy homeostasis; Early neuroprotection; 1,4-DPCA; 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid prolyl hydroxylase inhibitor elevating HIF-1αprotein level; AAT; Aspar
Keywords: گابار; 5HT3R; 5-hydroxytryptamine receptor, subtype 3; ATP; Adenosine triphosphate; BK; big potassium channels; Cho; cholesterol; CTD; C-terminal domain; ECD; extracellular domain; ELIC; Erwinia chrysanthemi ligand-gated ion channel; GABAAR; gamma-aminobutyric a
Keywords: گابار; CCCs; cation-chloride transporters; GABAAR; GABAA receptors; SE; status epilepticus; CA1; cornus ammonis 1; DG; dentate gyrus; aCSF; artificial cerebrospinal fluid; sulfo-NH-SS-biotin; sulfosuccinimidyl-2-[biotinamido]ethyl-1,3-dithiopropionate; PBS; phos
Keywords: گابار; [Ca++]i; intracellular Ca2+ concentration; 2ME2; 2-methoxyestradiol, a natural metabolite of estradiol; 4-OH-Tmx; 4-hydroxytamoxifen, a metabolite of Tmx; 5-HT3R; 5-hydroxytryptamine receptor subtype 3; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropio
Keywords: گابار; MD; molecular dynamics; CG; coarse-grained; NMR; nuclear magnetic resonance; ESR; electron spin resonance; EM; electron microscopy; POPC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPG; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol; POPE; 1-pa
Keywords: گابار; Ketamine; Depression; NMDAR; GluN2B; AMPAR; Ambient glutamate; Cortex; Inhibition; Disinhibition; NMDA receptor; AMPA receptor; Homeostatic synaptic plasticity; Protein synthesis; Folimycin (PubChem CID: 6438151); Glutamate (PubChem CID: 33032); Ketamine
Keywords: گابار; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AUD; alcohol use disorder; FDA; Food and Drug Administration; GABAAR; γ-aminobutyric acid receptor; NAc; nucleus accumbens; nAChRs; nicotinic acetylcholine receptors; NMDA; N-methyl-d-aspartate
Keywords: گابار; AA; all-atom; AD; Alzheimer's disease; AFM; atomic force microscopy; BK channels; big potassium channels or large conductance, Ca2+- and voltage-gated K+ channels; CCM; cholesterol consensus motif; CG; coarse-grained; CRAC; cholesterol recognition/interac
Keywords: گابار; CGP; CGP 35348; ECF; extracellular fluid; GABAAR; GABAA receptor; GABABR; GABAB receptor; GLNECF; extracellular glutamine; GLUECF; extracellular glutamate; HC; hippocampus; Extracellular glutamine; Extracellular glutamate; Disinhibition; Rat hippocampus;
Keywords: گابار; Cys-loop receptor; Pentameric ligand-gated ion channel; Phosphorylation; Conformational changes; Drug discovery; 5-HT3R; 5-hydroxytryptamine type-3 receptor; CamKII; Ca2+/calmodulin-dependent protein kinase; GABAAR; GABA type-A receptor; GlyR; glycine rec
Keywords: گابار; Amyotrophic lateral sclerosis; Spinal motor neuron degeneration; Inhibitory circuits; GABA; Glycine; Acetylcholine; Renshaw cell; ALS; amyotrophic lateral sclerosis; SOD1; superoxide dismutase type 1; FALS; familial amyotrophic lateral sclerosis; SALS; sp
Keywords: گابار; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor; BDNF; brain derived neurotrophic factor; BLA; basolateral amygdala complex; BZD; benzodiazepine; CeA; central amygdala nucleus; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; COR V; laye
Keywords: گابار; 3Br7NI; 3-bromo-7-nitroindazole; AEDs; antiepileptic drugs; AMPA; DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; CGP39551; (E)-(±)-2-amino-4-methyl-5-phospho no-3-pentenoic acid ethyl ester; CBZ; carbamazepine; CP46502
Keywords: گابار; ADP; afterdepolarization; AHP; afterhyperpolarization; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EGTA; ethylene glycol tetraacetic acid; GABAAR; GABAA receptor; GABABR; GABAB receptor; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; ISI; interspi
Flavones-bound in benzodiazepine site on GABAA receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin
Keywords: گابار; Flavones; GABAAR; Anxiety and memory; PM-DAT;
GABAA receptor: Positive and negative allosteric modulators
Keywords: گابار; γ-Aminobutyric acid type A receptors; Inhibitory neurotransmission; CNS depressant drug target; Anxiolytics/sedatives/general anesthetics; Ethanol; GABA; γ-aminobutyric acid; GABAAR; GABAA receptors; LGIC; ligand-gated ion channels; PLGIC; pentameric LG
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity
Keywords: گابار; Antipsychotic; Excitatory-inhibitory imbalance disorders; GABAAR; Prefrontal transmission; Quercetin; AAV; Adeno-associated virus; ACSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DAPI; 4,6-d
GABAA Receptor Subtypes Regulate Stress-Induced Colon Inflammation in Mice
Keywords: گابار; Alprazolam; IBD; Inflammatory Response; THIP; α3-/-; γ-aminobutyric acid subtype A receptor α3 gene-deleted mice; CD163; cluster of differentiation 163; ELS; early-life stress; ENS; enteric nervous system; FITC; fluorescein isothiocyanate; GABA;
Effect of phenol on the GABAAR-coupled Clâ/HCO3â-ATPase from fish brain: An in vitro approach on the enzyme function
Keywords: گابار; GABAAR; GABAA receptor; PMP; Plasma membrane-enriched preparation; PEP; Purified enzyme preparation; hrCNE-PAGE; High resolution clear native Electrophoresis; SDS-PAGE; Sodium dodecyl sulfate polyacrylamide gel electrophoresis; Phenol; Clâ/HCO3â-ATPas
Uric acid and allopurinol aggravate absence epileptic activity in Wistar Albino Glaxo Rijswijk rats
Keywords: گابار; A2AR; A2A type of adenosine receptors; CNS; central nervous system; COX-1 and COX-2; cyclooxygenase 1 and 2; EEG; electroencephalogram; GABAAR; GABAA type of gamma-aminobutyric acid receptors; IL-1; interleukin-1; IMP; inosine monophosphate; i.p.; intrape
Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits
Keywords: گابار; Dendritic inhibition; Presynaptic inhibition; Network activity; Electron microscopy; Synaptic plasticity; Ion channels; BC; basket cell; CA; cornu ammonis; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cAMP; cyclic adenosine monophosphate; Cav chan
Peripheral GABAA receptor-mediated signaling facilitates persistent inflammatory hypersensitivity
Keywords: گابار; Complete Freund's adjuvant (CFA)-induced persistent inflammatory hypersensitivity; GABAAR; Endogenous GABA; Picrotoxin; Bicuculline; 3α,5α-THP; GABA; gamma-aminobutyric acid; GABAAR; gamma-aminobutyric acid type A receptor; CFA; complete Freund's adjuva
4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric γ-aminobutyric acid receptor binding site
Keywords: گابار; Hydroxy-1,2,3-triazole; Bioisosterism; Scaffold hopping; GABAA receptor; GABA; γ-Aminobutyric acid; GABAAR; GABA type A receptor; 4-PIOL; 5-(piperidin-4-yl)-3-isoxazolol; 4-PHP; 4-(piperidin-4-yl)-1-hydroxypyrazole; aza-4-PIOL; 5-(piperidin-4-yl)-3-hydro
Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina
Keywords: گابار; Orexin; Retinal rod bipolar cell; GABA receptor; Neuromodulation; BCs; bipolar cells; BIC; bicuculline; Bis-IV; bisindolylmaleimide IV; CPPG; (RS)-α-cyclopropyl-4-phosphor- nophenylalycine; DAG; diacylglycerol; DLG; dorsal lateral geniculate nucleus; DT-
Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors
Keywords: گابار; Ago-PAM; allosteric agonist and positive allosteric modulator; C/R; concentration-response; ECD; extracellular domain; FMP; FLIPR Membrane Potential Blue; GABA; γ-Aminobutyric acid; GABAAR; GABAA receptor; methaqualone; 2-methyl-3-(o-tolyl)-quinazolin-4(
The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord
Keywords: گابار; [Ca2+]i; intracellular Ca2+ concentration; 5-HT; serotonin; Ach; acetylcholine; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin;
Neonatal inhibition of Na+-K+-2Clâ-cotransporter prevents ketamine induced spatial learning and memory impairments
Keywords: گابار; Anesthetic; Bumetanide; GABAAR; Ketamine; NKCC1; Neurotoxicity;
Bicuculline, a GABAA-receptor antagonist, blocked HPA axis activation induced by ghrelin under an acute stress
Keywords: گابار; GHS-R; growth hormone secretagogue receptor; HPA axis; hypothalamic-pituitary-adrenal axis; CRH; corticotropin-releasing hormone; AVP; arginin-vasopresin hormone; ACTH; adrenocorticotropic hormone; PVN; paraventricular nucleus; IMM; intermediate media
Research PaperAltered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia
Keywords: گابار; BDNF; brain-derived neurotrophic factor; CAVII; cytosolic carboanhydrase isotyp 7; GABAAR; GABAA receptor; IN; interneurons; PV; parvalbumin; KCC2; potassium chloride transporter 2; Basal ganglia; Fast spiking interneurons; Parvalbumin; GABA; Striatum; BD
Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors
Keywords: گابار; GABAergic; IPSC; Tonic inhibition; Synaptic inhibition; TB-21007; MRK-016; α5IA; L-655708; GABAAR; GABA type-A receptor; IPSC; inhibitory postsynaptic current; DMEM-FBS; Dulbecco's Modified Eagles Medium supplemented with 10% fetal bovine serum; TB-21007
Antibodies to AMPA receptors in Rasmussen's encephalitis
Keywords: گابار; Autoantibodies; Rasmussen's encephalitis; AMPA receptors; Abs; antibodies; AED; anti-epileptic drugs; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazolepproprionic acid receptor; BBB; blood brain barrier; CASPR2; contactin-associated protein receptor like 2; CBA
Broflanilide: A meta-diamide insecticide with a novel mode of action
Keywords: گابار; EBOB; 4â²-ethynyl-4-n-propylbicycloorthobenzoate; GABA; γ-aminobutyric acid; GABAAR; GABA type A receptor; GABAR; GABA receptor; GlyR; glycine receptor; GluCl; glutamate-gated channel; meta-diamides; 3-benzamido-N-(4-(perfluoropropan-2-yl)phenyl)benzami
Glycine blocks long-term potentiation of GABAergic synapses in the ventral tegmental area
Keywords: گابار; aCSF; artificial cerebrospinal fluid; DNQX; 6,7-dinitroquinoxaline-2,3-dione; eIPSC; evoked inhibitory postsynaptic current; GABA; gamma-aminobutyric acid; GABAAR; GABAA receptor; GlyR; glycine receptor; GLYTs; glycine transporters; HFS; high-frequency st
Enduring changes in tonic GABAA receptor signaling in dentate granule cells after controlled cortical impact brain injury in mice
Keywords: گابار; GABA; gamma-aminobutyric acid; ITonicGABA; tonic GABA current; GABAAR; type A GABA receptor; CCI; controlled cortical impact; DG; dentate gyrus; TBI; traumatic brain injury; DGC; dentate granule cell; THIP; 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-3-ol
Compromised GABAergic inhibition contributes to tumor-associated epilepsy
Keywords: گابار; GABAA receptor; GABAAR; glioblastoma multiforme; GBM; K+/Clâ co-transporter 2; KCC2; KA; kainic acid; NKCC1; Na-K-Cl co-transporter 1; Glioma; Tumor; Epilepsy; GABA; KCC2; Seizures;
The terpenoids Myrtenol and Verbenol act on δ subunit-containing GABAA receptors and enhance tonic inhibition in dentate gyrus granule cells
Keywords: گابار; GABAAR; gamma aminobutyric acid receptor; mIPSC; miniature inhibitory postsynaptic current; TTX; tetrodotoxin; THIP; 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol; GABAA receptor subunit; Terpenoids; Volatile odorants; Dentate gyrus granule cells; Tonic
A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABAA receptors: The challenge in comparing apples with oranges
Keywords: گابار; GABAAR; γ-amino butyric acid receptor type A; DS1 and DS2; Delta selective agents 1 and 2; ECD; extracellular domain; ICL; intracellular loop between TM3 and TM4; PAM; positive allosteric modulator; TMD; transmembrane domain; wt.; wild-type; GABAA recept
Minireview: Mode of action of meta-diamide insecticides
Keywords: گابار; DM-RDL; Drosophila RDL GABA receptor subunit; EBOB; 4â²-ethynyl-4-n-propylbicycloorthobenzoate; GABA; γ-aminobutyric acid; GABAAR; GABA type A receptor; GlyR; glycine receptor; GluCl; glutamate-gated chloride channel; 5-HT3 receptor; serotonin type-3 re
Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol
Keywords: گابار; EC; extracellular; EC2; effective concentration at 2% of maximal response; EC50; half-maximal effective concentration; GABAAR; γ-aminobutyric acid type A receptor; GlyR; glycine receptor; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IC; int
Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine
Keywords: گابار; CCTV; closed circuit television; EEG; electroencephalography; EPM; elevated plus maze; GABAAR; type A gamma-aminobutyric acid receptor; Ip; intraperitoneal; NOR; novel object recognition; PBS; phosphate buffered saline; SD; standard deviation; SE; status
Invited reviewInvestigating ion channel conformational changes using voltage clamp fluorometry
Keywords: گابار; Fluorescence; Voltage clamp; Ion channel; Conformational change; Protein structure; 6TM; 6 transmembrane; fUAA; fluorescent unnatural amino acid; GABAAR; GABA A-type receptor; GlyR; glycine receptor; LGIC; ligand-gated ion channel; MTS; methanethiosulphon
GABA transporters control GABAergic neurotransmission in the mouse subplate
Keywords: گابار; ACSF; artificial cerebrospinal fluid; BGT-1; betaine/GABA transporter; CGP55845; (2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid; EGTA; 5 ethyleneglycol-bis(2-aminoethylether)-N,N,Nâ²,Nâ²-tetraacetic acid, 2
Synaptic changes in GABAA receptor expression in the thalamus of the stargazer mouse model of absence epilepsy
Keywords: گابار; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; CT; corticothalamic; EEG; electroencephalogram; EM; electron microscopy; GABA; γ-aminobutyric acid; GABAAR; GABAA receptor; GAT-1; GABA transporter 1; mIPSC; miniature inhibitory pos
Plasma glucocorticoids differentially modulate phasic and tonic GABA inhibition during early postnatal development in rat spinal lamina II
Keywords: گابار; 3α5αNS; 3α5α-reduced neurosteroids; ACSF; artificial cerebrospinal fluid; BIC; bicuculline; CORT; corticosterone; FIN; finasteride; GABAAR; GABAA receptor; FIS; Fischer; GABA; γ-aminobutyric acid; GBZ; gabazine; GC; glucocorticoids; HPA; hypothalamic
GABAA receptors are located in cholinergic terminals in the nucleus pontis oralis of the rat: Implications for REM sleep control
Keywords: گابار; ACh; acetylcholine; BZ; benzodiazepine; GABAAR; type-A GABA receptor; GAD67; glutamic acid decarboxylase-67; KCC2; potassium-chloride cotransporter-2; MAP2; microtubule-associated protein 2; PB; phosphate buffer; PnO; oral pontine reticular formation; REM
The effects of avermectin on amino acid neurotransmitters and their receptors in the pigeon brain
Keywords: گابار; AVM; avermectin; CNS; central nervous system; GABA; γ-aminobutyric acid; NMDA; N-methyl-d-aspartate; NR1; NMDA receptor 1; NR2; NMDA receptor 2; NR2A; NMDA receptor 2A; NR2B; NMDA receptor 2B; GABAAR; GABA A receptor; GABABR; GABA B receptor; HPLC; high-