Identification of S100 calcium binding protein A9 as a prognostic biomarker in gallbladder cancer

The study shows that elevated expression and hypomethylation in the S100A9 gene promoter suggesting that DNA methylation plays a crucial role in the regulation of S100A9 expression in GBC. However, further studies are warranted to confirm this in larger pool of samples before concluding its usefulness as a biomarker of GBC.