کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8389219 1543950 2018 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Global DNA methylation and depression: Preliminary result from community based epidemiological study
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
Global DNA methylation and depression: Preliminary result from community based epidemiological study
چکیده انگلیسی
The present study aims to investigate the role of Global DNA Methylation in Depression. A total of 368 individuals (118 males and 250 females) were screened for depression using PHQ9 (Patient Health Questionnaire 9) and 5-mc% (5-methyl cytosine) content of Peripheral Leucocytes DNA was measured by enzyme linked calorimetric based MethyFlash™ methylated DNA quantification kit. Among individuals with depression a lower Global DNA methylation (though not significant) in terms of 5-mc% (5-methyl cytosine) content was observed compared to individuals without depression.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Meta Gene - Volume 15, February 2018, Pages 84-86
نویسندگان
, , , , ,