کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8403935 | 1544684 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ameliorative effect of chitosan-conjugated 17α-methyltestosterone on testicular development in Clarias batrachus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
Chitosan nanoparticles conjugated with 17α-methyltestosterone (CSâ¯+â¯MT) were used for studying their effect on the testicular development of Clarias batrachus during different reproductive phases. The size of chitosan nanoparticles was 127.2â¯nm and the nano-conjugated 17α methyltestosterone (17α-MT) was 196.1â¯nm (20â¯mg/100â¯ml of chitosan). Single injections of CSâ¯+â¯MT at different doses such as 0.01, 0.1 and 0.5â¯Î¼g/g body weight were administered to adults during the pre-spawning, spawning and post-spawning phase. Nano-conjugated steroid was effective at the lower dose; showing an increase in the Gonadosomatic Index (GSI) and 11-ketotestosterone level compared to the control group. Histological observations confirmed the dose-dependent advancement in spermatogenesis. These findings indicate the possibility of using CSâ¯+â¯MT for enhancing gonadal maturity of C. batrachus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Animal Reproduction Science - Volume 193, June 2018, Pages 245-254
Journal: Animal Reproduction Science - Volume 193, June 2018, Pages 245-254
نویسندگان
Ratnadeep Saha, Irfan Ahmed Bhat, Ravi Charan, Suresh Babu Padinhate Purayil, Gopal Krishna, Annam Pavan Kumar, Rupam Sharma,