کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8416728 1545649 2018 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stability of individual LPS-induced ex vivo cytokine release in a whole blood assay over a five-year interval
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Stability of individual LPS-induced ex vivo cytokine release in a whole blood assay over a five-year interval
چکیده انگلیسی
Repeatability of ex vivo cytokine reactivity showed to be differential for the measured cytokines, being more stable for IL-10 and IL-1β than for TNFα. However, in general, repeatability of ex vivo cytokine reactivity was weak, reflecting that cytokine reactivity can mostly be explained by (short term) intra-individual (immunological) or time varying environmental factors and less by genetic or other time-invariant factors. Therefore, WBA should be regarded as a viable tool to study relationships with current health status and exposure, and only partially as a predictor for a future response.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Immunological Methods - Volume 460, September 2018, Pages 119-124
نویسندگان
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