Oral immunization using HgbA in a recombinant chancroid vaccine delivered by attenuated Salmonella typhimurium SL3261 in the temperature-dependent rabbit model

► Salmonella typhimurium SL3261 as vaccine strain to immunize rabbits. ► Haemophilus ducreyi HgbA delivered as the vaccinogen. ► HgbA expression restricted to one day post immunization. ► No protective immunity induced.