کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8419139 | 1545734 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوتکنولوژی یا زیستفناوری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays](/preview/png/8419139.png)
چکیده انگلیسی
⺠Phage libraries ideal for rapid isolation of diagnostic antibodies in an emergency. ⺠We compared utility of synthetic scFv and natural Fab libraries for such purposes. ⺠All antibodies from Fab library could be rapidly expressed as full-length IgG. ⺠Majority of scFv library antibodies carry amber stops or CDR glycosylations. ⺠Screening Fab library therefore preferred method for rapid antibody development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Immunological Methods - Volume 373, Issues 1â2, 28 October 2011, Pages 79-88
Journal: Journal of Immunological Methods - Volume 373, Issues 1â2, 28 October 2011, Pages 79-88
نویسندگان
Conrad E.Z. Chan, Annie H.Y. Chan, Angeline P.C. Lim, Brendon J. Hanson,