Isolation of functional single domain antibody by whole cell immunization: Implications for cancer treatment

► Isolated from cancer cells immunized llama. ► Recognizes recombinant and native CEACAM6 antigen. ► Has a very high affinity (5 nM) to the antigen. ► Blocks pancreatic cancer cell proliferation. ► Gives a good in vivo image in mouse model of pancreatic cancer.