کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8429240 1546172 2017 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transformation of marginal zone lymphoma (and association with other lymphomas)
ترجمه فارسی عنوان
تبدیل لنفوم ناحیه حاشیه (و ارتباط با سایر لنفوم ها)
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Marginal zone lymphomas (MZL) are a diverse group of indolent lymphoproliferative disorders that comprise three subtypes: nodal, splenic and mucosal associated marginal zone lymphomas (MALT). Histologic transformation (HT) to an aggressive lymphoma is a rare event that can occur in any subtype, and at lower frequency compared to other indolent non Hodgkin lymphomas (NHL) like follicular lymphoma. There are few data directly associated with risk and prognosis of transformation in MZL. However, recent advances in the understanding of molecular and genetic features of MALT have contributed to an evolving appreciation of HT in this disease. Optimal treatment of HT of MZL remains unknown. Much of the approach to managing transformed MZL is extrapolated from other indolent NHLs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Haematology - Volume 30, Issues 1–2, March–June 2017, Pages 131-138
نویسندگان
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