Platinum-sensitivity in metastatic colorectal cancer: Towards a definition

A sensitive population of patients more likely to benefit from oxaliplatin reintroduction is defined by the efficacy of induction therapy followed by an OFI of at least 6 months between two periods of FOLFOX therapy. OFI of <6 months identifies a subgroup of partially-resistant patients who can still benefit from oxaliplatin reintroduction.