کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8459555 1548896 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evolution of treatment for nasopharyngeal cancer - Success and setback in the intensity-modulated radiotherapy era
ترجمه فارسی عنوان
تکامل درمان سرطان نازوفارنکس - موفقیت و شکست در دوره پرتودرمانی مدولاسیون شدت
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی
Significant improvement in survival and reduction of serious toxicity was achieved as we evolved from 2DRT to 3DRT and IMRT era; the therapeutic ratio for all T-categories improved with more conformal techniques. Improvements in tumor control were attributed not only to advances in RT technique, but also to better imaging and increasing use of potent chemotherapy. However, it should also be noted that hearing impairment significantly increased due to chemotherapy, L-FFR reached a plateau in the 3DRT era, and it is worrisome that the result for T4 remained unsatisfactory. Besides exploring for more potent chemotherapy and innovative methods, the guideline on dose constraint should be re-visited to optimize the therapeutic ratio.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiotherapy and Oncology - Volume 110, Issue 3, March 2014, Pages 377-384
نویسندگان
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