Immunomodulatory role of TIITS in respect to cytotoxic lymphocytes in four grades of human glioma

► Upregulation of cytotoxicity of T lymphocytes in T11TS treated in vitro grade I and II glioma. ► Significant enhancement of CD2, CD8 in T11TS treated in vitro lymphocytes of grade I and II glioma. ► Significant enhancement of CD25, CD56 in T11TS treated in vitro lymphocytes of grade I and II glioma. ► Upregulation of cytotoxic protein in T11TS treated lymphocytes of grade I and II glioma. ► Insignificant change between T11TS treated and non treated lymphocytes of grade III, IV glioma.