Fatty acid profile during the differentiation and infection with Mycobacterium tuberculosis of mononuclear phagocytes of patients with TB and healthy individuals

► Human classical and inflammatory monocytes have clear differences in their fatty acid profiles. ► TB patients have a higher number of inflammatory monocytes. ► The classical monocytes display a higher saturation levels. ► Lower saturation index correlated with susceptibility to membrane damage. ► Differentiation into macrophages also changes the fatty acid profile.