کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8471836 1550138 2007 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Étude comparative de neuf trousses de réactifs détectant des anticorps antiprotéines ou peptides citrullinés
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Étude comparative de neuf trousses de réactifs détectant des anticorps antiprotéines ou peptides citrullinés
چکیده انگلیسی
The aim of our study is to assess the analytical and diagnostic performances of 9 laboratory tests that identify citrullinated-proteins or peptides antibodies: anticyclic citrullinated peptides CCP2 (Inova, Eurodiagnostica and phadia's companies), anticyclic citrullinated peptides CCP3 (Inova's company), anticitrullinated recombinant rat filaggrin (Genesis'company), anticitrullinated vimentin (Orgentec's company), deiminated Epstein Barr virus nuclear antigen 1 (Astra's company) and deiminated fibrinogen (Pr Serre's home-made test). This study includes 102 patients suffering rheumatoid arthritis and tested positive to CCP2's Immunoscan test from Eurodiagnostica company. This study points out a noticeable difference in sensitivity depending upon the antigen substrates and also a different pattern of antibodies values' distribution around the cut-off area regarding each test. No correlation of numerical values has been found between these tests impeding any numerical prognostic values of a possible rheumatoid arthritis'severity form.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immuno-analyse & Biologie Spécialisée - Volume 22, Issue 4, August 2007, Pages 223-235
نویسندگان
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