Metabolomic analysis of two different models of delayed preconditioning

► First metabolomics study in two models of preconditioning. ► Two models of preconditioning have markedly disparity in metabolites signatures. ► Metabolomic of repetitive coronary stenosis is similar to hibernating myocardium. ► Energy metabolism, the more changed pathway in repetitive coronary stenosis. ► The traditional second window exhibited few changes and resembles sham.