کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8484842 1551621 2017 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Successful treatment of azole-resistant invasive aspergillosis in a bottlenose dolphin with high-dose posaconazole
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Successful treatment of azole-resistant invasive aspergillosis in a bottlenose dolphin with high-dose posaconazole
چکیده انگلیسی
Invasive aspergillosis due to azole-resistant Aspergillus fumigatus is difficult to manage. We describe a case of azole-resistant invasive aspergillosis in a female bottlenose dolphin, who failed to respond to voriconazole and posaconazole therapy. As intravenous therapy was precluded, high dose posaconazole was initiated aimed at achieving trough levels exceeding 3 mg/l. Posaconazole serum levels of 3-9.5 mg/l were achieved without significant side-effects. Follow-up bronchoscopy and computed tomography showed complete resolution of the lesions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Mycology Case Reports - Volume 16, June 2017, Pages 16-19
نویسندگان
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