کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8497606 | 1553544 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Heat shock factor 1 regulates heat shock proteins and immune-related genes in Penaeus monodon under thermal stress
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Heat shock factor 1 regulates heat shock proteins and immune-related genes in Penaeus monodon under thermal stress Heat shock factor 1 regulates heat shock proteins and immune-related genes in Penaeus monodon under thermal stress](/preview/png/8497606.png)
چکیده انگلیسی
Heat shock factors (HSFs) participate in the response to environmental stressors and regulate heat shock protein (Hsp) expression. This study describes the molecular characterization and expression of PmHSF1 in black tiger shrimp Penaeus monodon under heat stress. PmHSF1 expression was detected in several shrimp tissues: the highest in the lymphoid organ and the lowest in the eyestalk. Significant up-regulation of PmHSF1 expression was observed in hemocytes (pâ¯<â¯0.05) following thermal stress. The expression of several PmHsps was rapidly induced following heat stress. Endogenous PmHSF1 protein was expressed in all three types of shrimp hemocyte and strongly induced under heat stress. The suppression of PmHSF1 expression by dsRNA-mediated gene silencing altered the expression of PmHsps, several antimicrobial genes, genes involved in the melanization process, and an antioxidant gene (PmSOD). PmHSF1 plays an important role in the thermal stress response, regulating the expression of Hsps and immune-related genes in P. monodon.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 88, November 2018, Pages 19-27
Journal: Developmental & Comparative Immunology - Volume 88, November 2018, Pages 19-27
نویسندگان
Phornphan Sornchuer, Wisarut Junprung, Warumporn Yingsunthonwattana, Anchalee Tassanakajon,