Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways

Besides, wogonin derivatives are also developed to surmount its low bioavailability and to enhance its cytotoxicity to cancer cells. Wogonin pharmacokinetics and its side effects are also discussed in this review to figure out the metabolism of wogonin, the presence of this compound in animal models, and its safe range of applicable dose as well.