Meroterpenoid dimers from Ganoderma cochlear and their cytotoxic and COX-2 inhibitory activities

Spirocochlealactones A-C (1-3), three new spiro meroterpenoidal dimers, together with one known compound ganodilactone (4), were isolated from the fruiting bodies of Ganoderma cochlear. Their structures including absolute configurations were assigned by using spectroscopic methods and ECD calculations.113