Three new alkaloids from Xylopia vielana and their antiinflammatory activities

Three newaporphine alkaloids, xylopialoids A-C (1-3), along with three known aporphine alkioids (4-6), and three other known compounds (7-9) were isolated from the roots of Xylopia vielana. The structures of new compounds were determined by extensive NMR, MS and IR spectroscopic analysis. Besides the absolute configurations were also elucidated by CD spectrum and X-ray analysis. All thesix alkaloids were first tested for their anti-inflammatory activities.62