Association of functional SNP-1562CÂ >Â T in MMP9 promoter with proliferative diabetic retinopathy in north Indian type 2 diabetes mellitus patients

The present study suggests that the functional SNP-1562C > T in the promoter of the MMP-9 gene could be regarded as a major risk factor for PDR as increased MMP-9 production from high expressing T allele may promote retinal angiogenesis.