کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8645474 | 1569785 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Phylogenetic analysis of two goat-origin PCV2 isolates in China
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کلمات کلیدی
PCV1PCV2ORFsPCVADPPRVPCV3PDNSPorcine circovirus 3Peste des petits ruminants virus - Peste des petits معتادین ویروسGoat - بزphylogenetic analysis - تجزیه و تحلیل فیلوژنتیکGenetic diversity - تنوع ژنتیکیPorcine dermatitis and nephropathy syndrome - درماتیت گوسفند و سندرم نفروپاتیOpen reading frames - فریم های خواندن را باز کنیدcapsid protein - پروتئین کپسیدCaP - کلاه لبه دار
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Complete genome characterization of non-porcine origin Porcine circovirus type 2 (PCV2) was first described in 2014 in China. In the present study, we first identified PCV2 nucleotides in goat samples and the prevalence of PCV2 in goat was 6.15%. However, only two new strains, Goat2014-4 and Goat2014-5, could be completely sequenced. The genome of the strain Goat2014-4, which collected from the goat infected with PPRV, contains 1766â¯nt; strain Goat2014-5, which originated from a healthy goat, is comprised of 1767â¯nt. The results showed that they shared the highest nucleotide identity with BDH and the lowest similarity with DK1980PMWSfree strain and they belonged only to genotype PCV2d. Meanwhile, they shared higher homology with porcine-origin PCV2 strains than others. Moreover, a detailed analysis of the capsid amino acid sequences revealed that there were distinct differences for goat2014-4 (708â¯bp) and goat2014-5 (705â¯bp); strain Goat2014-4 showed an elongation of two amino acids, and strains Goat2014-5 showed an elongation of one amino acid compared with other reference strains. This is the first report of the genetic analysis of goat-origin PCV2 isolates. It also provides an additional supported evidence for cross-species transmission of PCV2.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 651, 20 April 2018, Pages 57-61
Journal: Gene - Volume 651, 20 April 2018, Pages 57-61
نویسندگان
Xiaomin Wang, Wenliang Li, Xianglan Xu, Wei Wang, Kongwang He, Hongjie Fan,