کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8646712 | 1570140 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of mammarenavirus infection (WÄnzhÅu virus) on the morphology of Rattus exulans
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
بوم شناسی، تکامل، رفتار و سامانه شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The circulation of mammarenaviruses in rodent populations of the Mekong region has recently been established, with a genetic variant of WÄnzhÅu virus, Cardamones virus, detected in two Rattus species. This study tests the potential teratogenic effects of WÄnzhÅu infection on the development of a Murid rodent, Rattus exulans. Using direct virus detection, morphological records and comparative analyses, a link was demonstrated between host infection status and host morphologies (the spleen irrespective of weight, the skull shape and the cranial cavity volume) at the level of the individual (females only). This study demonstrates that mammarenavirus infections can impact natural host physiology and/or affect developmental processes. The presence of an infecting micro-parasite during the development of the rat may lead to a physiological trade-off between immunity and brain size. Alternatively, replication of virus in specialized organs can result in selective morphologic abnormalities and lesions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Infection, Genetics and Evolution - Volume 63, September 2018, Pages 404-409
Journal: Infection, Genetics and Evolution - Volume 63, September 2018, Pages 404-409
نویسندگان
Jean Artois, Kim Blasdell, Veasna Duong, Philippe Buchy, Vibol Hul, Serge Morand, Julien Claude,