Pyrvinium Sensitizes Clear Cell Renal Cell Carcinoma Response to Chemotherapy Via Casein Kinase 1α-Dependent Inhibition of Wnt/β-Catenin

Our findings suggest that pyrvinium is a useful addition to the treatment armamentarium for clear cell RCC. Our work also demonstrate that targeting Wnt/β-catenin is a potential therapeutic strategy in clear cell RCC.