کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8662458 | 1576092 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sex-related differences in chronic heart failure
ترجمه فارسی عنوان
اختلالات مرتبط با جنسیت در نارسایی مزمن قلبی
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کلمات کلیدی
نارسایی قلبی، ارتباط جنسی، تفاوت،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
The prevalence of chronic heart failure (CHF) is steadily increasing. Both sexes are affected, with significant differences in etiology, epidemiology and clinical presentation, prognosis, comorbidities, and response to treatment. Women tend to develop CHF at a more advanced age, present more often with HF with preserved ejection fraction, are more symptomatic, and have a worse quality of life than men, but also a better prognosis. In women, CHF has more frequently a non-ischemic etiology, and arterial hypertension and diabetes mellitus are leading comorbidities. Furthermore, many sex-related differences have been detected in the response to treatment, for example a greater prognostic benefit from angiotensin-receptor blockers in women, a higher incidence of complications after defibrillator implantation, and a greater response to cardiac resynchronization therapy. Furthermore, women are less likely to receive defibrillator therapy or heart transplantation. The significant underrepresentation of women in clinical trials limits our capacity to evaluate the extent of sex-related differences in CHF, although their characterization seems crucial in order to achieve the ultimate goal of a tailored therapy for this condition.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 255, 15 March 2018, Pages 145-151
Journal: International Journal of Cardiology - Volume 255, 15 March 2018, Pages 145-151
نویسندگان
Alberto Aimo, Giuseppe Vergaro, Andrea Barison, Silvia Maffei, Chiara Borrelli, Doralisa Morrone, Matteo Cameli, Alberto Palazzuoli, Giuseppe Ambrosio, Stefano Coiro, Ketty Savino, Elisabetta Cerbai, Rossella Marcucci, Roberto Pedrinelli,