Evaluation of beat-to-beat ventricular repolarization lability from standard 12‐lead ECG during acute myocardial ischemia

Despite limitations imposed by signal quality, TWA and NARV are higher in patients with AMI, even after correction for potential confounders. The clinical value of TWA and NARV derived from standard ECG using our time-domain RMS method is questionable due to the small number of beats and significant noise.