کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8685588 | 1580271 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Improving the efficiency of Auditory Brainstem Responses in newborns, using a 60Â clicks/s stimulation rate
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
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چکیده انگلیسی
Recent evidence suggests that Auditory Brainstem Responses (ABR), in neonates with risk factors for neurological damage, may show auditory brainstem abnormalities, even in patients with normal hearing. To compare the recording and diagnostic accuracy of neonatal Auditory Brainstem Responses (ABR), using 10 and 60 clicks/s stimulation rates, two groups of neonates were prospectively studied: 30 healthy full-term neonates, with no peri- or postnatal complications; and 30 high-risk newborns with two or more of the following conditions: hyperbilirubinemia, use of ototoxic drugs, birth weight inferior to 1500 g, perinatal sepsis, intraventricular hemorrhage, and/or mechanical ventilation. Correlation between ABR trials, recording duration, and the absolute and interpeak latencies of ABR waves I, III and V, were measured. ROC-curve analysis assessed the diagnostic accuracy of both stimulation rates. The correlations between ABRs trials were significantly higher at 60 clicks/s than at 10 clicks/s (F(1,116) = 14.5, p < 0.0002). Recording duration at 60 clicks/s was significantly lower (t = 20.9, p < 0.0001). ROC-curve comparisons showed increased diagnostic accuracy at the stimulation rate of 60 clicks/s, for waves I (D = 2.04, p = 0.04), V (D = 2.02, p = 0.04), interpeak latencies III-V (D = 2.2, p = 0.02), and I-V (D = 2.86, p = 0.004). In neonates, the use of 60 clicks/s stimulation rate permits a substantial shortening of the ABR recording, with greater diagnostic accuracy and replicability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 45, November 2017, Pages 299-304
Journal: Journal of Clinical Neuroscience - Volume 45, November 2017, Pages 299-304
نویسندگان
Lourdes Cubero-Rego, Josefina Ricardo-Garcell, MarÃa Corsi-Cabrera, Rogelio Cruz-MartÃnez, Carlos Rebolledo-Fernández, Gloria Otero-Ojeda, ThalÃa Harmony,