کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8686659 1580830 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
On the importance of precise electrode placement for targeted transcranial electric stimulation
ترجمه فارسی عنوان
بر اهمیت قرار دادن الکترود دقیق برای تحریک الکتریکی ترانس مغناطیسی هدف
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی
Transcranial electric stimulation (TES) is an increasingly popular method for non-invasive modulation of brain activity and a potential treatment for neuropsychiatric disorders. However, there are concerns about the reliability of its application because of variability in TES-induced intracranial electric fields across individuals. While realistic computational models offer can help to alleviate these concerns, their direct empirical validation is sparse, and their practical implications are not always clear. In this study, we combine direct intracranial measurements of electric fields generated by TES in surgical epilepsy patients with computational modeling. First, we directly validate the computational models and identify key parameters needed for accurate model predictions. Second, we derive practical guidelines for a reliable application of TES in terms of the precision of electrode placement needed to achieve a desired electric field distribution. Based on our results, we recommend electrode placement accuracy to be < 1 cm for a reliable application of TES across sessions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 181, 1 November 2018, Pages 560-567
نویسندگان
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