کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8687060 | 1580838 | 2018 | 38 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Single multi-echo GRE acquisition with short and long echo spacing for simultaneous quantitative mapping of fat fraction, B0 inhomogeneity, and susceptibility
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
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چکیده انگلیسی
Multi-echo gradient echo (mGRE) sequences have been widely adapted in clinical and scientific practice for different purposes to their capability of performing Dixon MRI, generating multi-contrast images and extracting multi-parametric maps. This work aims to extend mGRE-based techniques for imaging whole head, where further technical developments are required due to the co-existence of fat and large B0 inhomogeneity in regions such as the skull base and neck. Specifically, bipolar mGRE data were acquired with a single sequence that contains both a short echo-spacing (ÎTE) echo train to capture water-fat and B0 phase shifts (for proton density fat-fraction (FF) and B0 mapping) and a longer ÎTE echo train (and long echo times) to capture subtle susceptibility variations and R2* information. The mGRE images covering the whole head (spatial resolution 1.0Â ÃÂ 1.0Â ÃÂ 2.0Â mm3) were acquired in 5Â min. An automated processing pipeline was implemented to use the FF and B0 maps determined from the short-TE train to compensate for the effects of fat, remove the background phase for whole-head quantitative susceptibility mapping, and reduce the difficulty of spatial phase unwrapping of the long echo-time data. Data from healthy volunteers imaged on a 3Â T scanner along with phantom validation are presented. Co-registered quantitative multi-parametric maps (FF, B0 inhomogeneity, R2*, local frequency shift and quantitative susceptibility) and multi-contrast images covering the whole head were successfully generated in processing times of several minutes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 172, 15 May 2018, Pages 703-717
Journal: NeuroImage - Volume 172, 15 May 2018, Pages 703-717
نویسندگان
Junmin Liu, Spencer D. Christiansen, Maria Drangova,