کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8687126 1580840 2018 59 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Functional atlas of the awake rat brain: A neuroimaging study of rat brain specialization and integration
ترجمه فارسی عنوان
آتلکتیک عملکرد مغز بیدار مغز: یک مطالعه عصبی تصویری از تخصص و یکپارچگی مغز موش صحرایی
کلمات کلیدی
اتصال حالت عملکرد حالت حالت استراحت، موش تقسیم کل مغز، تخصص ادغام،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
چکیده انگلیسی
Connectivity-based parcellation approaches present an innovative method to segregate the brain into functionally specialized regions. These approaches have significantly advanced our understanding of the human brain organization. However, parallel progress in animal research is sparse. Using resting-state fMRI data and a novel, data-driven parcellation method, we have obtained robust functional parcellations of the rat brain. These functional parcellations reveal the regional specialization of the rat brain, which exhibited high within-parcel homogeneity and high reproducibility across animals. Graph analysis of the whole-brain network constructed based on these functional parcels indicates that the rat brain has a topological organization similar to humans, characterized by both segregation and integration. Our study also provides compelling evidence that the cingulate cortex is a functional hub region conserved from rodents to humans. Together, this study has characterized the rat brain specialization and integration, and has significantly advanced our understanding of the rat brain organization. In addition, it is valuable for studies of comparative functional neuroanatomy in mammalian brains.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 170, 15 April 2018, Pages 95-112
نویسندگان
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