کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8693499 | 1581600 | 2018 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Albumin levels and cause-specific mortality in community-dwelling older adults
ترجمه فارسی عنوان
سطوح آلبومین و مرگ و میر ناشی از علت خاص در افراد مسن با مسن تر
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کلمات کلیدی
آلبومین، مرگ و میر محل اقامت جامعه بزرگسالان سالمند،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب مکمل و جایگزین
چکیده انگلیسی
To investigate the association between serum albumin levels and cause-specific mortality among community-dwelling older adults. This cohort study was based on data obtained from the government-sponsored Annual Geriatric Health Examination Program for the older adults in Taipei City between 2006 and 2010. The study sample consisted of 77,531 community-dwelling Taipei citizens (â¥65â¯years old). Mortality was determined by matching the participants' medical records with national death files. Serum albumin levels were categorized into <3.6, 3.6-3.7, 3.8-3.9, 4.0-4.1, 4.2-4.3, and â¥4.4â¯g/dL. Cox proportional hazards regression models were used to evaluate the association between albumin levels and cause-specific mortality. Spline regression was used to calculate the risk of mortality associated with albumin levels, modeled as continuous variables. Community-dwelling older adults had a mean albumin level of 4.3â¯g/dL, which significantly reduced by age. Compared to albumin levels â¥4.4â¯g/dL, mildly low albumin levels (4.2-4.3â¯g/dL) were associated with an increased mortality risk (hazard ratio [HR]: 1.16, 95% confidence interval [CI]: 1.05-1.28 for all-cause mortality), and albumin levels <4.2â¯g/dL were associated with significantly higher rates of all-cause, cancer, cardiovascular, and respiratory mortalities. In the spline regression, the curve of mortality risk was relatively flat at an albumin level â¥4.4â¯g/dL, and the mortality risk gradually increased as the albumin level declined. Albumin levels â¥4.4â¯g/dL were associated with better survival among community-dwelling older adults, and mortality risk increased as the albumin level decreased.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Preventive Medicine - Volume 112, July 2018, Pages 145-151
Journal: Preventive Medicine - Volume 112, July 2018, Pages 145-151
نویسندگان
Chen-Yi Wu, Hsiao-Yun Hu, Nicole Huang, Yi-Chang Chou, Chung-Pin Li, Yiing-Jenq Chou,