Vitamin D (25-OHD) deficiency may increase the prevalence of medication-related osteonecrosis of the jaw

Prevalence of MRONJ in AM treated patients seems to be increased by low serum 25-OHD. A measurable tendency in the role of 25-OHD for the development of MRONJ was recorded and leads to the recommendation for a sufficient vitamin D substitution in patients treated with AM.