کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8699559 | 1585495 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ovariectomy Exacerbates Apical Periodontitis in Rats with an Increase in Expression of Proinflammatory Cytokines and Matrix Metalloproteinases
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
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![عکس صفحه اول مقاله: Ovariectomy Exacerbates Apical Periodontitis in Rats with an Increase in Expression of Proinflammatory Cytokines and Matrix Metalloproteinases Ovariectomy Exacerbates Apical Periodontitis in Rats with an Increase in Expression of Proinflammatory Cytokines and Matrix Metalloproteinases](/preview/png/8699559.png)
چکیده انگلیسی
AP lesions in ovariectomized rats are larger and have an increased expression of proinflammatory cytokines and MMPs, indicating that the infection combined with ovariectomy has an important role in the regulation of these signaling molecules and enzymes during the development of AP. Based on that, it may be assumed that the hypoestrogenic condition aggravates inflammation and degradation of extracellular matrix components in AP, which may provide insight into understanding the development of AP in female postmenopausal patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Endodontics - Volume 44, Issue 5, May 2018, Pages 780-785
Journal: Journal of Endodontics - Volume 44, Issue 5, May 2018, Pages 780-785
نویسندگان
Priscilla Coutinho DDS, MS, PhD, MarÃlia P. DDS, MS, PhD, Francisco Wanderley G. DDS, MS, PhD, Graziela B. DDS, MS, PhD, Manoel D. DDS, MS, PhD, Raquel Assed B. DDS, MS, PhD, Lea Assed B. DDS, MS, PhD, Paulo DDS, MS, PhD,