کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
871783 910199 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hemodynamic transition driven by stent porosity in sidewall aneurysms
ترجمه فارسی عنوان
انتقال هتروترونیک به وسیله تخلخل استنت در آنوریسم های جانبی صورت می گیرد
کلمات کلیدی
همودینامیک، آنوریسم مغزی، استنت، گذار همودینامیک، دینامیک سیالات محاسباتی، سنجش ذرات ذرات
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی

The healing process of intracranial aneurysms (IAs) treated with flow diverter stents (FDSs) depends on the IA flow modifications and on the epithelization process over the neck. In sidewall IA models with straight parent artery, two main hemodynamic regimes with different flow patterns and IA flow magnitude were broadly observed for unstented and high porosity stented IA on one side, and low porosity stented IA on the other side. The hemodynamic transition between these two regimes is potentially involved in thrombosis formation. In the present study, CFD simulations and multi-time lag (MTL) particle imaging velocimetry (PIV) measurements were combined to investigate the physical nature of this transition. Measurable velocity fields and non-measurable shear stress and pressure fields were assessed experimentally and numerically in the aneurysm volume in the presence of stents with various porosities. The two main regimes observed in both PIV and CFD showed typical flow features of shear and pressure driven regimes. In particular, the waveform of the averaged IA velocities was matching both the shear stress waveform at IA neck or the pressure gradient waveform in parent artery. Moreover, the transition between the two regimes was controlled by stent porosity: a decrease of stent porosity leads to an increase (decrease) of pressure differential (shear stress) through IA neck. Finally, a good PIV–CFD agreement was found except in transitional regimes and low motion eddies due to small mismatch of PIV–CFD running conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 48, Issue 7, 1 May 2015, Pages 1300–1309
نویسندگان
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