Clinical Trials 101 in Pediatric Oncology Patients

Most children with cancer are enrolled in a clinical trial, as progress is still needed for better treatments and improved prognosis. This can include phase I, II, or III trials, which vary from unknown adverse effects to well-established data. In the emergency department, it is critical to know if a patient is participating in a clinical trial and any known details or complications from the treatment. The present article reviews the fundamental foundation of clinical trial phases, as well as possible adverse effects for patients enrolled on these studies.