Devices for endoscopic ultrasound-guided tissue acquisition

Endoscopic ultrasound-guided tissue acquisition (EUS-TA) has greatly evolved since the first EUS-guided fine-needle aspiration was reported 25 years ago. EUS-TA has become the procedure of choice for sampling of the pancreas, subepithelial lesions, and other structures adjacent to the gastrointestinal tract. Initial EUS devices were needles, primarily for performing fine-needle aspiration. Newer EUS devices have expanded the capabilities of the endosonographer to include TA for histologic evaluation, in vivo microscopy, fiducial placement, and EUS-based therapeutic interventions. This review will focus on the devices for use with EUS that are currently approved in the US including those for EUS-TA as well as other modalities.