کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8737190 | 1591325 | 2018 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Outcome of facial palsy from Lyme disease in prospectively followed patients who had received corticosteroids
ترجمه فارسی عنوان
نتیجه گیری از فلج صورت از بیماری لیم در آینده به دنبال بیماران که کورتیکواستروئیدهای دریافت کرده بودند
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی
Although a short course of corticosteroid therapy has been shown to improve the outcome of idiopathic facial nerve palsy (Bell's palsy), it is unclear whether corticosteroids, in addition to antibiotic therapy, are beneficial, are harmful, or have no impact on the outcome of facial palsy from Lyme disease (LDFP). From 2011 through 2016, 14 patients with LDFP were enrolled into a prospective study to determine the outcome of Lyme disease over the ensuing 12â¯months. Eleven (78.6%) had received corticosteroids in addition to oral antibiotics and entered the study within 24â¯days after onset of the LDFP (median 14â¯days, range 2-24â¯days). Overall, 6 of the corticosteroid-treated patients (54.5%, 95% C.I.: 28.0% to 78.7%) had evidence of residual dysfunction of the facial nerve at the last evaluation, which occurred at a mean of 13.1â¯months after the baseline visit (range 9.6-19.6â¯months). In conclusion, although corticosteroids are frequently prescribed for LDFP, the efficacy of this therapy has not been established. Like another recent report, our study raises concern about the safety of adjunctive corticosteroid treatment for LDFP. A well-designed, prospective clinical trial is needed to determine the risk-to-benefit ratio of corticosteroid therapy for LDFP.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 91, Issue 4, August 2018, Pages 336-338
Journal: Diagnostic Microbiology and Infectious Disease - Volume 91, Issue 4, August 2018, Pages 336-338
نویسندگان
Gary P. Wormser, Donna McKenna, Carol Scavarda, Carol Karmen,