Activity of ceftazidime-avibactam against carbapenemase-producing Enterobacteriaceae from urine specimens obtained during the infection-carbapenem resistance evaluation surveillance trial (iCREST) in Spain

- Overall prevalence of carbapenemase-producing Enterobacteriaceae (CPE) in urine specimens in Spain was 1.6%.
- Klebsiella pneumoniae was the most common isolate (87.8%).
- Distribution of CPE was as follows: OXA-48 (86.8%), KPC (6.9%), VIM (4.8%), NDM (1.1%) and IMP (0.6%).
- Ceftazidime-avibactam showed 100% susceptibility in KPC and OXA-48 producers.