کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8738776 | 1591735 | 2017 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Extended-spectrum β-lactamase-producing Enterobacteriaceae colonisation in long-term care facilities: a systematic review and meta-analysis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
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چکیده انگلیسی
The objectives of this study were to estimate the colonisation rate by extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) among residents of long-term care facilities (LTCFs) and to identify pertinent risk factors. A systematic search of PubMed and EMBASE databases for studies published up to May 2016 that provided raw data for gastrointestinal colonisation by ESBL-PE among LTCF residents was performed. Twenty-three studies reporting data on 9775 screened subjects met the inclusion criteria. The pooled prevalence of ESBL-PE among LTCF residents was 18% [95% confidence interval (CI) 12-24%]. Risk factors for colonisation included recent antibiotic use (within 6 months) [odds ratio (OR)â=â2.06, 95% CI 1.78-2.38], previous hospitalisation (within 2.5 years) (ORâ=â1.50, 95% CI 1.04-2.15), history of invasive procedures (within 2 years) (ORâ=â2.79, 95% CI 1.66-4.70), previous ESBL-PE colonisation or infection (ORâ=â6.77, 95% CI 1.33-34.62), history of urinary tract infection (ORâ=â2.66, 95% CI 1.76-4.01) and urinary catheter use (ORâ=â2.55, 95% CI 1.29-5.04). In conclusion, almost one in five LTCF residents is colonised with ESBL-PE, and colonised residents are more likely to have a history of recent antibiotic use or healthcare facility utilisation. Strict adherence to antimicrobial stewardship in LTCFs is needed to address these high resistance rates.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 50, Issue 5, November 2017, Pages 649-656
Journal: International Journal of Antimicrobial Agents - Volume 50, Issue 5, November 2017, Pages 649-656
نویسندگان
Myrto Eleni Flokas, Michail Alevizakos, Fadi Shehadeh, Nikolaos Andreatos, Eleftherios Mylonakis,